thanks for your question. No, it does not - as long as you are able to upload your files, which is easy with iweb or any FTP software, you are good to go!

does it matter if I use a mac. if so, what is the best web hosting site using a mac? thanks!

I think 1 and 1 is the best web hosting companies out there to day and I've tried tons of them from there to the really expensive ! ( I've bee with 1and 1 for almost a year now and I have never had any down times or any other problems with service and/or site(server) errors!